Mg(ClO 4) 2 catalyzed Eco-benign synthesis of 1,2,4-triazolinone derivatives as anti-tubercular agents
Dorababu Atukuri , Pramod Kattimani and Ravindra Kamble
Department of Chemistry, Karnatak University, Pavate Nagar, Dharwad-580003, India.
Abstract: An eco-benign approach towards the synthesis of 1,2,4-triazolinones incorporated with isoindoline-1,3-dione (4a-j) and 9H-fluoren-9-imine (5a-j) was carried out using sydnones (1a-j) as synthon under magnesium perchlorate as catalyst . The newlysynthesized compounds were screened for anti-tubercular activities.
Keywords: Sydnone; isoindoline-1,3-dione; fluroenone; Mg(ClO 4) 2 ; antitubercular activity. |