Organotin(IV) compounds of n-propyl and isopropyl glutarate: their synthesis, spectral characterization and antibacterial activity
Javid Hussain, Hidayat Hussain, Viqar Uddin Ahmad, Ahmed Al-Harrasi and Amin Badshah
Department of Chemistry, Kohat University of Science and Technology Kohat, Khyber Pakhtunkhwa, Pakistan
Department of Biological Sciences and Chemistry, PC 616, University of Nizwa, Nizwa, Sultanate of Oman
H.E.J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi 75270, Pakistan
Department of Chemistry, Quaid-e-Azam University, Islamabad, Pakistan
Abstract: A series of new di- and triorganotin(IV) complexes of monoisopropyl and mono n-propyl glutarate have been synthesized and characterized by 1H- 13C- 119Sn-NMR, UV, IR and Mass spectrometry. The spectroscopic investigation demonstrated that the carboxylate group acts as a bidentate ligand in diorganotin(IV) and as a monodentate ligand in triorganotin(IV) compounds. Biological evaluation against various microorganisms indicates that the diorganotin(IV) complexes are slightly less reactive than triorganotin(IV) complexes.
Keywords: Organotin(IV) carboxylates; spectroscopic studies; biological activity . |