Ethyl coumarin-3-carboxylate: synthesis and chemical properties
Bakr F. Abdel-Wahab, Hanan A. Mohamed and Abdelbasset A. Farhat
Chemistry department, Faculty of Science & Arts, King Abdel-Aziz University, Khulais, Kingdom of Saudi Arabia
Applied Organic Chemistry Department, National Research Center, Dokki, Giza, Egypt
Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt
Abstract – Ethyl coumarin-3-carboxylate occupies an important position in the organic synthesis and is used in production of biologically active compounds. Thus, the data published over the last few years on the methods of synthesis and chemical properties of ethyl coumarin-3-carboxylate are reviewed here for the first time. The reactions were classified as coumarin ring reactions and ester group reactions, and some of these reactions have been applied successfully to the synthesis of biologically and industrially important compounds.
Keywords: Ethyl coumarin-3-carboxylate; synthesis; chemistry. © 2014 ACG Publications. All rights reserved. |