Nano-TiO 2 catalyzed microwave synthesis of α -Hydroxyphosphonates
S. Siva Prasad, S. H. Jayaprakash, K. Umamaheswara Rao, N. Bakthavatchala Reddy, P. Chenna Rohini Kumar and C. Suresh Reddy
Department of Chemistry, Sri Venkateswara University, Tirupati - 517 502, India
Abstract: A simple, novel and green method is reported for the synthesis of α-hydroxyphosphonates by hydro-phosphonylation of various structurally diversified aldehydes (aromatic/ heteroaromatic) using Nano-TiO 2 as catalyst under solvent free microwave condition. Environmentally benign reaction procedures, short reaction times, easy work-up, high product yields, and reusability of catalyst for several cycles with consistent activity makes this protocol a highly attentive one.
Keywords: α -Hydroxyphosphonates; Nano-TiO 2 ; Hydro-phosphonylation; microwave. © 2014 ACG Publications. All rights reserved.
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