Amberlyst-15: An Efficient and reusable heterogeneous catalyst for the synthesis of β-amino carbonyl compounds

Pathakota Venkata Ramana, Kunda Uma Maheswara Rao, Balam Satheesh Krishna, Soora Harinath Jayaprakash, Shaik Ahammed Kabeer, Kaveti Sudheer and Cirandur Suresh Reddy

Department of Chemistry, Sri Venkateswara University, Tirupati - 517 502, India

Department of Applied Chemistry, Graduate School of Engineering & Resource Science, National University Corporation, Akita University, Akita-010-8502, Japan

Department of Chemistry, PES University, Bangalore - 560 085, India

Abstract: A simple and efficient method has been developed for the synthesis of β-amino carbonyl compounds from aromatic ketones, aldehydes and amines by Mannich reaction in the presence of amberlyst-15 as a reusable heterogeneous catalyst at room temperature under solvent-free conditions. The noteworthy advantages of the present method are short reaction times, good product yields, simple procedures and use of non-toxic catalyst.

Keywords: β -Amino carbonyl compounds; Amberlyst-15; Mannich reaction. © 2015 ACG Publications. All rights reserved.