Simple synthesis of non-symmetric 1,4-dialkoxybenzenes via 4-alkoxyphenols

Motyka Radosław, Stecko Sebastian and Suwiński Jerzy W.

Department of Physical Chemistry and Technology of Polymers, Marcina Strzody 9, 44-100 Gliwice, Poland

Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland

Centre of Polymer and Coal Materials, Polish Academy of Sciences, Marii Skłodowskiej-Curie 34, 41-819 Zabrze, Poland

Abstract: A three steps synthesis of non-symmetric 1,4-dialkoxybenzenes starting from 4-hydroxybenzaldehydes was described. At first step 4-alkoxyphneols were alkylated to give 4-alkoxybenzaldehydes. At the second step 4-alkoxybenzaldehydes were submitted to a Baeyer-Villiger oxidation with 30% H 2O 2 to afford 4-alkoxyphenols. At the last step 4-alkoxyphenols were secondly alkylated to give the title compounds.

Keywords: 4-alkoxyphenols; 1,4-dialkoxybenzenes; monomer; PPV; synthesis. © 2016 ACG Publications. All rights reserved.