Bioactivity and Chemical Composition of the Leaf Essential Oil of Talauma gloriensis Pittier (Magnoliaceae) from Monteverde , Costa Rica
William A. Haber, Brittany R. Agius, Sean L. Stokes, William N. Setzer
Rec. Nat. Prod. (2008), 2:1; 1-5
1 Missouri Botanical Garden , St. Louis , Missouri 63166 , USA Apdo. 50-5655, Monteverde, Puntarenas , Costa Rica , Central America
2 Department of Chemistry, University of Alabama in Huntsville , Huntsville , AL 35899 , USA
Abstract: The leaf essential oil of Talauma gloriensis was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). The most abundant essential oil components were myrcene (31.7%) and germacrene D (43.5%). The leaf oil showed notable brine shrimp toxicity (LC 50 = 14.1 µg/mL) and slight cruzain inhibitory activity (IC 50 = 98.6 µg/mL), but was devoid of cytotoxic activity or antibacterial activity.
Key words: Talauma gloriensis ; essential oil composition; myrcene; germacrene-D; brine shrimp lethality; cruzain inhibition |