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Chemical Constituents of Klainedoxa gabonenses and Paullinia pinnata

Etienne Dongo, Hidayat Hussain, Renadin S. Miemanang, Dagobert Tazoo, Barbara Schulz, Karsten Krohn

Department of Organic Chemistry, Faculty of Science, Yaounde I University, P. O Box 812, Yaounde, Cameroon.

Department of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany

Institut für Mikrobiologie, Technische Universität Braunschweig, Spielmannstraße 7, 31806 Braunschweig, Germany

Abstract: From the whole plant of Klainedoxa gabonenses betulinic acid (1), lupeol (2), ß-sitosterol (3), β-amyran-3-one (4) and 3,3',4'-tri-O-methylellagic acid (5) were isolated. Similarly paullinomide A (6), β-amyrin (7), 2-(4-hydroxy-3,5-dimethoxyphenyl)-3-hydroxymethyl-2,3-dihydro-1,4,5-trioxaphenanthren-6-one (8), 5α-poriferastane-3ß,6α-diol (9), β-sitosterol (3), l-quebrachitol (10), and ß-sitosterol glucopyranoside (11) were isolated from roots of Paullinia pinnata. Preliminary studies showed that 2-(4-hydroxy-3,5-dimethoxyphenyl)-3-hydroxymethyl-2,3-dihydro-1,4,5-trioxaphenanthren-6-one (8) showed moderate algicidal activity against the alga Chlorella fusca

Keywords: Paullinia pinnata ; Klainedoxa gabonenses; algicidal activity .