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Secondary Metabolites of Curvularia oryzae MTCC 2605

Siddhardha Busi, Prabhakar Peddikotla, Suryanarayana M. Upadyayula,Venkateswarlu Yenamandra

Biology Division, Indian Institute of Chemical Technology, Tarnaka, Hubsiguda, Hyderabad 500 007, Andhra Pradesh, India

Organic Chemistry Division-I, Indian Institute of Chemical Technology, Tarnaka, Hubsiguda, Hyderabad 500 007, Andhra Pradesh, India

Abstract: Curvularia oryzae MTCC 2605 was exploited for the production of secondary metabolites. The major compounds from the crude extract were purified by silica gel column chromatography and identified to be 11-α-methoxycurvularin and (S)-5-ethyl-8, 8-dimethylnonanal by NMR and Mass spectral data. Bioassays showed that 11-α-methoxycurvularin was active against bacteria, fungi and 4th instar Spodoptera litura larvae.

Keywords: Curvularia oryzae; 11-α-methoxycurvularin; antibacterial; antifungal; antilarval.

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