10.

Flavonoids and Terpenoids from Phlomis cashmeriana and their Chemotaxonomic significance

Javid Hussain, Nousheen Bukhar, Naseem Bano, Hidayat Hussain, Abdul Naeem andIvan R Green

Department of Chemistry, Kohat University of Science and Technology N.W.F.P, Pakistan

Department of Chemistry, Universität Paderborn, Warburger Straße 100, 33098 Paderborn, Germany

National Centre of Excellence in Physical Chemistry, University Peshawar, Peshawar, Pakistan

Department of Chemistry, University of the Western Cape, Bellville, 7530, South Africa

Abstract: The study of the chemical constituents of the whole plant of Phlomis cashmeriana ( Lamiaceae) has resulted in the isolation and characterization of twelve compounds. These twelve compounds were identified as apigenin 7,4'-dimethyl ether (1), luteolin-7-methyl ether (2), bitalgenin (3), kaempferol 3-O-3'''-acetyl- α -L-arabinopyranosyl-(1'''-6''')- β -D-glucopyranoside (4), glutinol (5), oleanolic acid (6), β -amyrin (7), ursolic acid (8), 3-O-p-coumaroylshikimic acid (9), 3 β -hydroxycycloart-24-one (10), and a mixture of β -sitosterol (11), and stigmasterol (12) . The above compounds were individually identified by spectroscopic analyses and comparisons with reported data. The chemotaxonomic studies of isolated compounds have been discussed. This study constitutes the first phytochemical work on P. cashmeriana

Keywords: Phlomis cashmeriana ; Lamiaceae; Natural Products; Chemotaxonomic studies.