Records of Natural Products

Year: 2012  Volume: 6  Issue: 1

 

  ORIGINAL ARTICLE

2.

A New Epimeric Sesquiterpene Lactone from Achillea ligustica

Ahmed A. Mahmoud 1, Shar S. Al-Shihry 1 and Mohamed-Elamir F. Hegazy

Department of Chemistry, College of Science, King Faisal University, P.O. Box 380, Hofuf 31982, Saudi Arabia

Chemistry of Medicinal Plants Department, National Research Center, Dokki, Giza 12622, Egypt

Abstract: A new sesquiterpene guaianolide (1) and two known compounds matricarin (2) and 5-hydroxy-5,6-secocaryophyllen-6-one (3) were isolated from the methylene chloride/methanol (1:1) extract of the aerial parts of Achillea ligustica All. The structure was determined on the basis of comprehensive 1D and 2D (COSY, NOESY, HMQC, HMBC) NMR and MS analyses.

Keywords: Achillea ligustica; Asteraceae; guaianolide.