16.

Chemical Composition and Antibacterial Activity of Essential Oils from Different Parts of Bupleurum rotundifolium L.

Mehtap Akın , Hatice Taner Saraçoğlu, Betül Demirci , Kemal Hüsnü Can Başer and Mustafa Küçüködük

Faculty of Science, Department of Biology, Selçuk University, 42075 , Konya, Türkiye

Faculty of Pharmacy, Department of Pharmacognosy, Anadolu University, 26470, Eskişehir, Türkiye

Abstract: The composition of the essential oils obtained by hydrodistillation from different parts of Bupleurum rotundifolium L. including roots, flowers and fruits were investigated by GC and GC/MS systems, simultaneously . The antibacterial activity of the oils was assessed with micro-dilution assays. The results showed large variations in the composition of the oils. The main components of the plant were undecane (26.4%) and tridecane (12.3%) in roots, hexadecanoic acid (12.2%) in flowers and α-pinene (11.0%) in fruits. The essential oils of B. rotundifolium obtained from flowers and fruits used in the study did not have any effect against bacteria. MIC values for the bacterial strains tested, which were sensitive to the essential oil of roots of B. rotundifolium , were in the ratio of 2 mg/mL. This investigation showed that the antibacterial activity of B. rotundifolium was attributed to the essential oil of roots, thus they can be a potential medicinal resource.

Keywords:Bupleurum rotundifolium ; essential oil composition; antibacterial activity; α-pinene; hexadecanoic acid.