Three New Compounds from the Marine Fungal Strain Aspergillus sp. AF119
Shaosong Liu, Chunhua Lu, Jing j ing Huang and Yue m ao Shen
Key Laboratory of the Ministry of Education for Cell Biology and Tumor Cell Engineering, Xiamen Engineering Research Center of Marine Microbial Drug Discovery, Fujian Engineering Laboratory for Pharmaceuticals ; School of Life Sciences, Xiamen University, No.422 South Siming Road, Xiamen, Fujian 361005, P. R. China
Abstract: Three new compounds, namely barceloneic lactone B (1) and barceloneic acid C (2) and 5’ -hydroxychlorflavonin ( 3 ), together with one known compound chlorflavonin ( 4 ), were isolated from the marine fungal strain Aspergillus sp. AF119. Their structures were elucidated by spectroscopic analyses including 1D- and 2D NMR experiments, and HR Q-TOF mass spectrometry. The antifungal activities against Candida albicans of these compounds were evaluated.
Keywords: Barceloneic lactone ; barceloneic acid ; chlorflavonin ; Aspergillus sp. AF119. |