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Secondary Metabolites from Halostachys caspica and Their Antimicrobial and Antioxidant Activities

Hao Liu, Kui Wang, Jianglin Zhao, Mingan Wang and Ligang Zhou

College of Agronomy and Biotechnology, China Agricultural University, Beijing 100193, China

C ollege of Science, China Agricultural University, Beijing 100 193 , China

Abstract: Nine secondary metabolites have been isolated from the aerial parts of Halostachys caspica C. A. Mey. (Chenopodiaceae). By means of physicochemical and spectrometric analysis, they were identified as betaine (1), diphenylamine (2), benzyl-O-β-D-glucopyranoside (3), β-sitosterol (4), 4-hydroxy-3-methoxy benzoic acid (5), 4-hydroxy benzoic acid (6), 2-hydroxy benzoic acid (7), 4-hydroxy-3,5-dimethoxy benzoic acid (8), and 3,4-dihydroxy benzeneacrylic acid (9). All compounds were isolated from this plant species for the first time. They were screened to exhibit antimicrobial and antioxidant activities to some extent except for the compounds 1 and 3. The results indicated that the isolated phenol acids and diphenylamine (2) could be the main bioactive components in the crude ethanol extract of H. caspica.

Keywords: Chenopodiaceae; Halostachys caspica; secondary metabolites; antimicrobial activity; antioxidant activity.