Isolation and Structure Elucidation of a New Triterpenoid from Prunus cerasoides D. Don
Liaqat Ali and Farzana Shaheen
HEJ Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan
Department of Biological Sciences and Chemistry, University of Nizwa, Birkat Al-Mauz, Nizwa-616, Oman
Abstract: One new metabolite, prunol (1), belonging to the pentacyclic triterpenoid skeleton was purified from the dichloromethane soluble fraction of the crude ethanolic extract of Prunus cerasoides D. Don. The structure elucidation was accomplished on the basis of one dimensional 1H and 13C NMR and two dimensional HMQC, HMBC, and COSY experiments. The molecular mass was determined by HRFAB-MS, while the major fragments were observed in the EI-MS. The comparative analysis of the NMR spectral data with the known analogues and the NOESY experiments were helpful in assigning the stereo centers in the molecule.
Keywords: Pentacyclic triterpenoids; Prunus cerasoides; ethanolic extract; NMR spectral data . |