13.

Secondary Metabolites of Centaurea cadmea Boiss.

Kaveh Alizadeh Astari, Sura Baykan Erel, Erdal Bedir and Canan Karaalp

Department of Pharmaceutical Botany, Faculty of Pharmacy, Ege University, 35100 Bornova-Izmir, Türkiye

Department of Bioengineering, Faculty of Engineering, Ege University, 35100 Bornova-Izmir, Türkiye

Abstract: Chlorogenic acid (1), scutellarin (2), syringin (3), 6S, 9R-roseoside (4) and b -sitosterol-3- O - b - D-glucopyranoside (5) were isolated from the aerial parts of Centaurea cadmea Boiss. (Asteraceae). S tructure elucidation of the compounds were performed by using spectroscopic methods (1-D and 2-D NMR and LC-MS-MS). To the best of our knowledge, compounds 1 , 2, 3 and 4 have been isolated for the first time from this endemic species. C ompound 4 is new for the genus Centaurea.

Keywords: Centaurea cadmea; chlorogenic acid; scutellarin ; syringin; roseoside; NMR.