5.

Two New Saccharide Fatty Acid Esters from the Fruit of Morinda citrifolia L. and Their ABTS Radical Scavenging Activities

Hong-Cai Zhang, Yu Wang, Chun-Miao Yu, Dong-Hua Yu, Ping-Ping Chen and Shu-Min Liu

Academy of Traditional Chinese Medicine, Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin 150040, China ,

College of Pharmacy, Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin 150040, China,

Drug Safety Evaluation Center, Heilongjiang University of Chinese Medicine, Harbin 150040, China

Abstract: Two n ew saccharide fatty acid esters (1) and (2), and six other compounds were isolated from the fruit of Morinda citrifolia L. (Rubiaceae) The structures were established as (2E)-oct-2-enoate-2-O-β-D - glucopyranosyl-β-D-glucopyranoside(1), (2E)-2,6-dimethyl -6-hydroxyl-oct-2,7-dienoate-2-O-β-D-glucopyranosyl-β-D-glucopyranoside(2), saccharumoside C(3), O-β-D-apiofuranosyl-(1→6)-O-β-D-glucopyranosides of 3-methyl-2-butenol(4), 3-methyl-but-2-en-1-yl β-D-glucopyranosyl (1→6)-β-D-glucopyranoside(5), benzyl - glucopyranoside(6), Hexyl-O-β-D-glucopyranoside(7), and caproic acid(8). Compound 1 and 2 showed moderate activity against ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonate)) radical in concentration of 0.1-3.2 mg/mL.

Keywords: Morinda citrifolia L.; saccharide fatty acid ester; ABTS radical scavenging activity. © 2014 ACG Publications. All rights reserved.