A New Cytotoxic Alkenylresorcinol from Embelia schimperi
Blanche L. Ndontsa, Faustine L. M. Dongmo, Michel F. Tala, Hippolyte K. Wabo, Guang-Zhi Zeng, Ning-Hua Tan and Pierre Tane
Department of Chemistry, University of Dschang, P.O. Box 67, Dschang, Cameroon
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, P.R. China
Abstract: An investigation of MeOH extract of Embelia schimperi stem led to the isolation of a new resorcinol derivative, 5-(7’Z-pentadecenyl)resorcinol (1), along with the known compounds lupeol (2) and β-sitosterol glucoside (3). The structures of isolated compounds were elucidated using spectroscopic methods. Compound 1 exhibited moderate in vitro cytotoxic activity against human Hela cell line.
Keywords: Embelia schimperi ; Myrsinaceae; alkenylresorcinol; 5-(7’Z-pentadecenyl)resorcinol; cytotoxic activity. © 2014 ACG Publications. All rights reserved. |