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Structural Elucidation of a New Sesquiterpene Alcohol by Comparative NMR Studies
Luiz Gustavo de Lima Guimarães, Maria das Graças Cardoso, Esther Maria Ferreira Lucas, Matheus Puggina de Freitas, Welington Francisco and David Lee Nelson
Departamento de Ciências Naturais, Universidade Federal de São João del Rei, 36.301-160, São João del Rei, MG, Brazil
Departamento de Química, Universidade Federal de Lavras, CEP 37.200-000, Lavras, MG, Brazil
Centro Federal de Educação Tecnológica de Minas Gerais, CEFET-MG, 30.421-169, Belo Horizonte, MG, Brazil
Colegiado de Química Ambiental, Universidade Federal do Tocantins, Campus de Gurupi, 77.402-970, Gurupi, TO, Brazil
Faculdade de Farmácia, Universidade Federal de Minas Gerais, 31270-901, Belo Horizonte, MG, Brazil
Abstract: The principal constituent of the essential oil from the leaves of the Cordia verbenacea plants collected in Minas Gerais, Brazil had a GC retention time similar to that of α-bisabolol, a sesquiterpene alcohol with important biological properties. NMR analyses ( 1H, 13C, DEPT-135, COSY, HMQC and HMBC) comparing the purified compound with α-bisabolol compound revealed that the new alcohol is an isomer structural of α-bisabolol, due to change in relation to the position of the double bond and the methyl group present in the cyclic chain of these compounds.
Keywords: Sesquiterpene alcohol; Cordia verbenacea;α-bisabolol; NMR . © 2015 ACG Publications. All rights reserved. |