Chemical Composition and Biological Activity of Essential Oils of Sempervivum brevipilum Muirhead Nuran Kahriman, Zeynep Şenyürek, Vildan Serdaroğlu, Aydın Kahriman and Nurettin Yaylı Department of Chemistry, Faculty of Sciences, Karadeniz Technical University, 61080, Trabzon, Türkiye Department of Forest Engineering, Faculty of Forestry, Artvin Çoruh University, 08000, Artvin, Türkiye Faculty of Pharmacy, Karadeniz Technical University, 61080, Trabzon, Türkiye Abstract: The essential oils of the fresh flower, leaf, and stem of Sempervivum brevipilum Muirhead. (Crassulaceae) were isolated by hydrodistillation in a modified Clevenger-type apparatus, and characterized by GC-FID and GC-MS. A total of fifty, fourty-three, and thirty-one compounds were identified, constituting over 92.6%, 92.6%, and 94.3% of oil composition of the flower, leaf, and stem of S. brevipilum, respectively. The chemical profile reveals the dominance of hydrocarbons (flower: 65.3%, leaf: 47.6%, stem: 71.1%). The major compounds of essential oils from S. brevipilum were tetracosane (20.2%) in flower, 1,2-diphenyl ethandione (16.1%) in leaf and docosane (30.5%) in stem. Monoterpene hydrocarbons were the major class of terpenoids in flower (2.2%) and in stem (1.8%), oxygenated diterpene was the major class of terpenoids in leaf (4.5%). Oxygenated monoterpenes were in minor amounts in all parts (flower: 0.3%, leaf: 0.7%, stem: 0.1%) of the plant. In addition, antimicrobial activities of the essential oils of S. brevipilum were investigated. The oils didn’t show any antibacterial and antifungal activity against tested bacteria, but showed high antituberculostatic activity against Mycobacterium smegmatis. Keywords: Crassulaceae; Sempervivum brevipilum; Essential oil; GC-FID; GC-MS. © 2015 ACG Publications.All rights reserved. |
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