23.

Characterization and Isolation of a New Flavonoid from Viburnum grandiflorum

Ghias Uddin, Muhammad Alam, Bina S. Siddiqui, Nizam Uddin, Anwar Sadat, Ashfaq Ahmad Khan and Naveed Muhammad

Institute of Chemical Sciences; Centre for Phytomedicine and Medicinal Organic Chemistry, University of Peshawar, Peshawar, Pakistan

H.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan

Department of Pharmacy, Abdul Wali Khan University Mardan 23200, Pakistan

Abstract: In the present study a new flavoniod 1 along with Betulin 2 Betulinic acid 3, Oleanolic acid 4 andUrsolic acid 5 were isolated from the aerial part of Viburnum grandiflorum Wall. ex DC as white amorphous powder from the chloroform fraction. On the bases of different modern spectroscopic techniques such as EIMS, UV, IR, NMR, HSQC, HMBC, COSY and NOESY the structure of compound 1 was elucidate as 6,7-bis (propenyloxy)-2-ethoxy-5-hydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one (Grandinoid).

Keywords: Viburnum grandiflorum; g randinoid . © 2014 ACG Publications. All rights reserved.