14.

A New 8′ ,9 ′ -Dinor 8,4 ′ -Oxy neolignan Glucoside from Dendrobium Aurantiacum var. Denneanum

Xiao-hong Li, Li Guo , Cheng Peng, Jin - hui Bian, Ting-mo Zhang, Cheng-jun He, Qin-mei Zhou and Liang Xiong

State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China

School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, P. R. China

Sichuan Wan'an Dendrobe Industry Development Co., Ltd, Chengdu, P. R. China

Abstract: An investigation of n-BuOH extract of Dendrobium aurantiacum var. denneanum stems has led to the isolation of a new 8′,9′-dinor 8,4′-oxyneolignane glucoside, (–)-(7 S ,8 S )-4-hydroxy-3,3′,5,5′-tetramethoxy-8′,9′-dinor - 8,4′-oxyneolign a -7,9-diol- 7 ′-al 4-O-β-D-glucopyranoside (1), and four phenylpropanoid glycosides (2– 5 ) . The structures of the isolated compounds were elucidated by chemical and spectroscopic methods . This is the first report of norlignane from the genus Dendrobium.

Keywords: Dendrobium aurantiacum var. denneanum ; norlignane ; oxy neolignan glucoside; phenylpropanoid glycoside . © 2015 ACG Publications. All rights reserved.