11.

Pyrrolizidine Alkaloids from Onosmakaheirei Teppner (Boraginaceae)

Ioanna Maria Orfanou, Harilaos Damianakos, Ioannis Bazos, Konstantia Graikou and Ioanna Chinou

Department of Pharmacy, Division of Pharmacognosy and Natural Product Chemistry, University of Athens, 15771 Greece

Department of Biology, Division of Ecology and Systematics, University of Athens, 15771 Greece

Abstract: The new pyrrolizidine alkaloid (PA) 3΄-O-acetylechinatine N-oxide (7), along with two more known PAs (5, 6), two known flavonoids (3, 4), one known alkannin (1), two known triterpenoids, one known sterol, and allantoin (2) were isolated from the aerial parts of Onosma kaheirei. In addition, the retention indeces of the reduced PAs 6 and 7 were determined in a DB-5 WCOT column, to aid their detection by GC/MS in the future.

Keywords: Boraginaceae; Onosma kaheirei; 3΄-O-acetylechinatine N-oxide; pyrrolizidine alkaloids; alkannins. © 2015 ACG Publications. All rights reserved.