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Phenolic Constituents from Alchornea castaneifolia

Michał Gleńsk, Jan A. Gliński, Marta Jamróz, Piotr Stefanowicz and Sławomir Kaźmierski

Wroclaw Medical University, Department of Pharmacognosy, Borowska 211 A , 50-556 Wrocław, Poland

Planta Analytica LLC, 39 Rose Street, Danbury, CT 06810, USA

Medical University of Warsaw, Department of Physical Chemistry, Faculty of Pharmacy, 1 Banacha Street, 02-097 Warsaw, Poland

University of Wroclaw, Faculty of Chemistry, F. Joliot-Curie 14, 50-383 Wrocław, Poland

The Centre of Molecular and Macromolecular Studies, Polish Academy of Science, Sienkiewcza 112, 90-363 Łódź, Poland

Abstract: Alchornea castaneifolia is a tree growing commonly in several South American countries. It is best known under its Peruvian name Iporuru. The leaves are being used as a folk remedy against numerous symptoms associated with pain and inflammation. It has a reputation for being a tonic and booster of male libido. In this study, using a combination of chromatographic techniques, we isolated phenolic constituents present in leaves, and elucidated their structures using MS and NMR techniques. The isolated and characterized compounds were myricetin glucoside, myricetin galactoside, proanthocyanidin A1 and A2, epicatechin, gallic acid, shikimic acid, putranjivain A, elaeocarpusin and never before isolated methyl ester of repandusinic acid A.

Keywords: Alchornea castaneifolia ; phenolics ; ellagitannins ; spectroscopic techniques; methyl ester of repandusinic acid A . @ 2015 ACG Publications. All rights reserved.