8.

Two New Phenolic Compounds from Schizonepeta tenuifolia (Benth.) Briq

Xu-Hua Huang, Jian-Hua Shao, Chun-Chao Zhao, Jia Chen, Xiu-Hua Shan, Xiao-Qing Xu and Wen-Ting Zhang

College of Biosci ence and Biotech nology , Yangzhou Univ ersity , Yangzhou 225009, China

Second affiliated hospital of Baotou medical college, Baotou, Inner Mongolia 014030, China

Abstract: Two new phenolic compounds, Schitenoside A (1) and Schitenoside B (2), have been isolated together with six known compounds: 3,4-dihydroxyphenethyl alcohol-4-O-β-D-glucopyranoside (3), 2-(3-hydroxy-4-methoxyphenyl) ethanol 1-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (4), benzyl 7-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside (5), 2-hydroxybenzoic acid (6), m-hydroxybenzoic acid (7) and trans-caffeic acid (8), from the Schizonepeta tenuifolia. Their structures were elucidated by spectroscopic analysis. Compounds (3-7) were isolated from Schizonepeta genus for the first time. Compounds 1 and 2 showed a week antibacterial activity against four test strains, involving both Gram-positive and Gram-negative bacteria .

Keywords : Lamiaceae; Schizonepeta tenuifolia; phenolic compounds; antibacterial activity . © 2016 ACG Publications. All rights reserved.