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Commicarpiflavonol Glucosides A and B; Two New 5-Deoxyflavonol Glucosides from Commicarpus grandiflorus

Dina R. Abou-Hussein, Ahmed M. Galal, Ikhlas A. Khan and Essam Abdel-Sattar

Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia

Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El-Aini, Cairo 11562, Egypt

National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA

Department of Biomolecular Sciences, Division of Pharmacognosy, School of Pharmacy, University of Mississippi, University, MS 38677, USA

Abstract: The phytochemical investigation of the aerial parts of Commicarpus grandiflorus ( Standl.) resulted in the isolation of two new flavonol 3-O-glucosides, commicarpiflavonol glucoside A (1) and commicarpiflavonol glucoside B (2), along with the known compounds β-sitosterol (3) and betulinic acid (4). The structures of the isolated compounds have been elucidated by extensive 1D ( 1H, 13C) and 2D (COSY, HSQC, HMBC) NMR spectral data analysis, as well as high-resolution mass determinations.

Keywords:Commicarpus grandiflorus; Nyctaginaceae; flavonol glycosides; commicarpiflavonol glucosides. © 2016 ACG Publications. All rights reserved.