8.

Chemical Composition and Antimicrobial Activity of Essential Oil of Lepechiniaradula Benth Epling

Vladimir Morocho, María Luisa Toro, Luis Cartuche, Diana Guaya, Eduardo Valarezo, Omar Malagón and Jorge Ramírez

Universidad Tecnica Particular de Loja / Seccion Quimica Basica y Aplicada, Departamento de Quimica, San Cayetano alto, calle Marcelino Champagnat, s/n. AP: 11 01 608, Loja-Ecuador

Universidad Tecnica Particular de Loja / Seccion Ingenieria de Procesos, Departamento de Quimica, San Cayetano alto, calle Marcelino Champagnat, s/n. AP: 11 01 608, Loja-Ecuador

Abstract: The essential oil (EO) was obtained by hydrodistillation from the aerial parts of Lepechiniaradula Benth Epling (Lamiaceae) from Ecuador. Thirty-four compounds accounting to 93.4% of the total oil were identified. The main constituents of the essential oil were δ-3-carene (19.9%), β-pinene (17.0%), (E)-β-caryophyllene (9.7%) and (E-E)-α-farnesene (9.4%). The essential oil of L.radula possessed strong antifungal activity against Trichophytonrubrum (ATCC® 28188) and Trichophytonmentagrophytes (ATCC® 28185).

Keywords: Lepechinia radula ; Lamiaceae; δ-3-carene; Trichophyton rubrum; Trichophyton mentagrophytes. © 2016 ACG Publications. All rights reserved.