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Soulieoside R : A New Cycloartane Triterpenoid Glycoside from Souliea vaginata

Qiongyu Zou , Jinping Shen, Yindi Zhu, Guoxu Ma , Xudong Xu, Yilin Liu, Zhenghong Luo, Zijian Zhao, Dizhao Chen and Haifeng Wu

Key Laboratory of Hunan Province for Study and Utilization of Ethnic Medicinal Plant Resources, Department of Chemistry & Chemical Engineering, Huaihua University, Huaihua 418008, P. R. China

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, P. R. China

State Key Laboratory of Herbs Detoxification Combination, School of Public Health, Peking University, Beijing 100191, China

School of Pharmacy, Wenzhou Medical University, Wenzhou 325035, P.R. China

Abstract: A new cycloartane triterpenoid glycoside, named soulieoside R, was isolated from the rhizomes of Souliea vaginata. Its structure was characterized by comprehensive analyses of 1H, 13C NMR, COSY, HSQC, HMBC, NOESY spectroscopic, and HRESIMS mass spectrometric data, as well as chemical methods. The new compound showed weak inhibitory activity against three human cancer cell lines.

Keywords: Souliea vaginata ; cycloartane triterpenoid; soulieoside R; cytotoxicity. © 2017 ACG Publications. All rights reserved.