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Phytochemistry and Pharmacology of Genus Indigofera: A Review

Taj Ur Rahman, Muhammad Aurang Zeb, Wajiha Liaqat, Muhammad Sajid, Sajjad Hussain and M. Iqbal Choudhary

Department of Chemistry, Mohi-Ud-Din Islamic University, AJ&K, Pakistan.

Department of Biochemistry, Hazara University, Mansehra, Pakistan

Institute of Chemical Sciences, University of Peshawar, Peshawar 25120, K.P.K, Pakistan

International Center for Chemical and Biological Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan

Abstract: In this review, the existing literature data on the phytochemical and biological studies of the genus Indigofera are outlined with 71 references. Up till now, 65 compounds were secluded from various species of genus Indigofera. The chemical components are mostly terpenoids, flavonoids and nitro group containing compounds, together with steroids and others. The metabolites and crude extracts of the genus indigofera were found to exhibit various bioactivities including, antimicrobial, insecticidal, phytotoxic, antiulcergenic, hepatotoxic, teratogenic and cytotoxicity. Other constituents isolated from the genus Indigofera displayed inhibitory activity against the enzyme lipoxygenase and gastrointestinal activity. This review represents a brief description of the total Phytochemical and Pharmacological activities of genus Indigofera as well as chemotaxonomic classification of chemical constituents

Keywords: Phytochemistry; Indigofera; bioactivity; pharmacology. © 2017 ACG Publications. All rights reserved