Records of Natural Products

Year: 2018 Volume: xx   Issue: x

 

  ORIGINAL ARTICLE

1.

Chemical Constituents and Antibacterial Activity of Essential Oils from Flowers and Stems of Ageratum conyzoides from Ivory Coast

Bi Koffi François P. Kouame, Daouda Toure, Landry Kablan, Gustave Bedi, Illa Tea, Richard Robins, Jean Claude Chalchat and Felix Tonzibo

LCOSN, UFR SSMT, 08 BP 582 Abidjan 08, Université F. H. B. Abidjan, Côte d’Ivoire

EBSI Group, CEISAM, University of Nantes–CNRS UMR6230, BP 92208, 44322 Nantes, France

UFR des Sciences Biologiques, Université P. G. C. Korhogo, BP 1328 Korhogo, Côte d’Ivoire

Laboratoire de Bactériologie-Virologie, Institut Pasteur, 01 BP 490 Abidjan 01, Côte d’Ivoire

Laboratoire de chimie des Hétérocycles et des Glucides Chimie des huiles essentielles, Les Cezeaux, 63177, Aubière France

Abstract: The essential oils (EOs) obtained by hydro-distillation of flowers and stems of Ageratum conyzoides L. ( Asteraceae) growing in Ivory Coast were investigated. The oils were analyzed and characterized by GC and GC–MS. Analyses of the EOs led to the identification and quantification of 48 constituents in the flower oil and 44 from the stem oil, respectively. Characterization of the EOs revealed the predominance of 6-demethoxyageratochromene or precocene I (flower: 58.8%, stem: 76.5%) and the sesquiterpene β -caryophyllene (flower: 15.2%, stem: 8.1%) . Six of the identified compounds β -copaene, hexanal, trans-cadina-1(6),4-diene, α -calacorene, caryophylla-4(12),8(13)-diene-5-β-ol and 1,10-di-epi-cubenol are reported for the first time as constituents of A. conyzoides . Comparative analysis with data from Nigeria, Pakistan, Fiji and Brazil is reported. The antibacterial activity of EOs from of A. conyzoides was tested against seven bacteria. The inhibition zones and minimum inhibitory concentration (MIC) for bacteria strains which were sensitive to A. conyzoides EOs were in the range of 6.7 to 12.7 mm and 64 to 256 μg/mL, respectively. The EOs showed moderate activity against Staphylococcus aureus and Enterococcus faecalis .

Keywords: Ageratum conyzoides , essential oils, flowers, stems, precocene I , antibacterial activity, Ivory Coast. © ACG Publication. All rights reserved.