JOURNAL


Bioorganic & Medicinal Chemistry Reports
VOLUME & ISSUE
Year: 2018 Issue: 1 January-December
PAGES
p.16 - 21
STATISTICS
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AUTHORS
  • Busra Olcel Dur
  • Recep Ozen
  • Furkan Ayaz
  • 1 - Mersin University Faculty of Arts and Science, Department of Chemistry, Türkiye
  • 2 - Mersin University Faculty of Arts and Science, Department of Chemistry, Türkiye
  • 3 - Mersin University Faculty of Arts and Science, Department of Biotechnology, Türkiye
PDF OF ARTICLE

ABSTRACT


Citric acid is an inactive ingredient that is widely used in pharmaceutical, cosmetic and food industries. It is an organic acid that is produced during the Krebs cycle of the cell metabolism therefore it is present in the living organisms. Natural resource of the citric acid is citrus fruits and it is well known for its preservative action. Synthetically by utilizing from biotechnological tools, it can be produced by Aspergillus niger in a media that can supply the sugar source. In this study we compared the efficiencies of carob molasses and potato based broths to grow A. niger for citric acid production. Carob molasses are widely found in the region and their utilization as media in biotechnological production of the citric acid would be advantageous. Our results support that this media can be used as an efficient source for the citric acid producing fungus A. niger in the bioreactors.

KEYWORDS
  • Microbiology
  • Biotechnology
  • Citric acid
  • Carob
  • Pharmaceutical industry
  • Cosmetics