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Chemical Constituents from Typhonium giganteum Rhizome and Their Antioxidant, Tyrosinase Inhibitory Activities

Original Article

JOURNAL 1741

Records of Natural Products
VOLUME & ISSUE
Year: 2021 Issue: 1 January-February
PAGES
p.53 - 58
DOI ADDRESS
http://doi.org/10.25135/rnp.196.20.07.1741
STATISTICS
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AUTHORS
  • Penghua Shu
  • Wenhan Yi
  • Yingying Fei
  • Mengyuan Sun
  • Yueyue Lou
  • Anqi Liu
  • Shujing Cai
  • Ruihua Li
  • Junping Li
  • Xialan Wei
  • Na Sun
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Fourteen constituents were isolated from the rhizome of Typhonium giganteum, which included two new compounds, trans-3,5-dihydroxy-cinnamyl alcohol (1), bis(2-ethylbutyl) terephthalate (2), along with twelve known compounds (3–14). The structures of these compounds were elucidated by physical data analyses such as 1D NMR, 2D NMR and HRESIMS. All compounds were tested for their antioxidant and tyrosinase inhibitory activities. Compounds 1, 5 exhibited obvious DPPH radical scavenging activities, while compounds 1, 5, 8, and 14 showed significant tyrosinase inhibitory activities.

 KEYWORDS
  • Typhonium giganteum
  • terephthalate
  • DPPH
  • tyrosinase

SUPPORTING INFORMATION

Supporting Information
Download File A6-196-RNP-2007-1741-SI.pdf (922.42 KB)