JOURNAL 1664


Records of Natural Products
VOLUME & ISSUE
Available Online: June 28,2020
PAGES
p.1 - 5
DOI ADDRESS
http://doi.org/10.25135/rnp.188.20.05.1664
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Rong Yao
  • Shen Yao
  • Ailian Hua
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Chemical investigation of the EtOAc extract of a marine-derived fungus Aspergillus versicolor SZW-5 led to the isolation of one new compound, named aspeverether A (1), and seven known compounds. The structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, and HRESIMS). Compounds 1 and 3 possessed an unusual 1,3-dimethoxy-2-vinylbenzene moiety, which is rarely found in nature. Compound 6 showed strong inhibitory effect toward a-glucosidase with an IC50 value of 71 mM, being more active than the positive acarbose (210 mM).

KEYWORDS
  • Aspergillus versicolor
  • aspeverether A
  • structure elucidation
  • marine

SUPPORTING INFORMATION


Supporting Information
Download File 188-RNP-2005-1664-SI.pdf (1.25 MB)