JOURNAL 3776
Records of Natural Products
VOLUME & ISSUE
Year: 2026 Issue: 3
Year: 2026 Issue: 3
PAGES
p.6 - 6
p.6 - 6
STATISTICS
Viewed 271 times.
Viewed 271 times.
AUTHORS
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Shulei Wan
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Jiamin Yin
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Feng-Qing Xu
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Jin-Song Liu
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Deling Wu
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Manqin Yang
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Renzhong Wang
GRAPHICAL ABSTRACT
ABSTRACT
Two new cucurbitane-type triterpenoids (1-2) and one known compound (3) were obtained from the ethyl acetate extract of Trichosanthes kirilowii Maxim. The structures of these compounds were elucidated on the basis of spectroscopic data analysis and comparison with spectroscopic data in the literature. All compounds were evaluated for anti-inflammatory activity in LPS-induced RAW264.7 cells. Compounds 1 and 2 could inhibit the secretion of IL-6, TNF-α, and NO, with IC50 values ranging from 34.82±1.54 to 86.14±1.94 μM
KEYWORDS- Trichosanthes kirilowii
- triterpenoids
- anti-inflammatory
