JOURNAL 2017


Records of Natural Products
VOLUME & ISSUE
Available Online: June 03,2021
PAGES
p.1 - 8
DOI ADDRESS
http://doi.org/10.25135/rnp.256.21.03.2017
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Bui Van Thanh
  • Nguyen Thi Van Anh
  • Chu Thi Thu Ha
  • Do Hoang Giang
  • Truong Thi Lien
  • Ninh Khac Thanh Tung
  • Nguyen Tien Dat
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A novel 2,3-dioxygenated flavanone, dysosmaflavanone (2), along with five known phenolic compounds including podophyllotoxin (1), podoverin A (3), kaempferol (4), 8,2′-diprenyl quercetin 3-methyl ether (5), and ethyl β-D-glucoside (6) were isolated from the roots of the plant Dysosma difformis. Their structures were elucidated via spectroscopic analysis. Besides podophyllotoxin and kaempferol, the rest of the compounds were isolated from the genus Dysosma for the first time. Dysosmaflavanone, which possesses a rare 2,3-dioxygenated skeleton, could be regarded as an important chemotaxonomic marker. The antioxidant and antidiabetic activities of the isolated compounds were evaluated.

KEYWORDS
  • Dysosma difformis
  • Berberidaceae
  • 2,3-dioxygenated flavanone
  • dysosmaflavanone

SUPPORTING INFORMATION


Supporting Information
Download File 256-RNP-2103-2017-SI.pdf (1.66 MB)