JOURNAL 2685
Records of Natural Products
VOLUME & ISSUE
Available Online: March 22,2023
Available Online: March 22,2023
PAGES
p.1 - 5
p.1 - 5
DOI ADDRESS
http://doi.org/10.25135/rnp.384.2301.2685 (DOI number will be activated after the manuscript has been available in an issue.)
http://doi.org/10.25135/rnp.384.2301.2685 (DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
Viewed 684 times.
Viewed 684 times.
GRAPHICAL ABSTRACT
ABSTRACT
A new ingenane diterpenoid, named ingenol-20-laurate (1), and two known analogues (ingenol-20-palmitate (2), ingenol-20-pentadecanoate (3)) and an ent-abietane diterpenoid (euphopilolide, 4) were isolated from the whole plants of Euphorbia jolkinii. The structure of compound 1 was elucidated by HRESIMS and 2D NMR methods. The cytotoxicities of compound 1 against SMMC-7721, MDA-MB-231, and SW480 cell lines were 27.22±0.58, 17.69±0.29 and 16.19±0.77 μM, respectively.
KEYWORDS- Euphorbia jolkinii
- diterpenoids
- cytotoxicities
