A New Sesquiterpene and Two Nitro-containing Phenylpropionic Acid Derivatives from the Fungus Aspergillus terreus LPFH-1
Records of Natural Products
Available Online: January 07,2023
p.1 - 6
http://doi.org/10.25135/rnp.375.2211.2623 (DOI number will be activated after the manuscript has been available in an issue.)
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Chemical study of the fungal strain Aspergillus terreus LPFH-1 led to the isolation of 8 compounds (1-8), including a new acyclic sesquiterpenoid (1) and two new natural products (2 and 3). Their structures were determined by extensive analyses of the spectroscopic data including 1D (1H and 13C NMR) and 2D NMR (1H-1H COSY, HSQC, HMBC, NOESY) data. Compounds 2 and 3 were nitro-containing phenylpropionic acid derivatives, whose absolute configuration was determined by comparing their specific rotations with those of synthetic products. The known compounds were identified as 4-hydroxy-3-(3-methylbut-2-enyl)benzaldehyde (4), ethyl 2,4-dihydroxy-5,6-dimethylbenzoate (5), terretonin D (6), asperterpene K (7), and asterrelenin (8).
- Aspergillus terreus
- marine-derived fungus
- new sesquiterpenes
- phenylpropionic acid