JOURNAL 2663
Records of Natural Products
VOLUME & ISSUE
Available Online: March 04,2023
Available Online: March 04,2023
PAGES
p.1 - 6
p.1 - 6
DOI ADDRESS
http://doi.org/10.25135/rnp.381.2212.2663 (DOI number will be activated after the manuscript has been available in an issue.)
http://doi.org/10.25135/rnp.381.2212.2663 (DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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Viewed 250 times.
GRAPHICAL ABSTRACT
ABSTRACT
A novel phenanthrene compound, diphenanthrin (1), and an undescribed alkaloid compound, N-chloromethylstephenanthrine (2), together with two known compounds (3-4) were isolated from the EtOH extract of the roots of Stephania tetrandra. Their structures were elucidated by 1D and 2D NMR, mass spectroscopy and comparison of NMR data with those of known compounds. In anti-inflammatory assay, compounds 3 and 4 showed the inhibitory effects on NO production, with IC50 values of 41.51 ± 0.20 and 23.87 ± 2.12 μM.
KEYWORDS- Stephania tetrandra
- phenanthrene
- alkaloid
- anti-inflammatory
