JOURNAL 2039


Records of Natural Products
VOLUME & ISSUE
Available Online: June 07,2021
PAGES
p.1 - 8
DOI ADDRESS
http://doi.org/10.25135/rnp.257.21.04.2039
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
Viewed 26 times.
AUTHORS
  • Yue Li
  • Jun Chi
  • Ping Wang
  • Lingxia Zhang
  • Qingxia Li
  • Qingmei Feng
  • Liping Dai
  • Zhimin Wang
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new isoflavonoid glycoside, achyranthoside C (1), along with two known compounds (2 and 3) were isolated from the rhizomes of Achyranthes bidentata. Compounds 1-2 were two rare natural isoflavonoid glycosides with C8 hydroxymethylene derivatization. Their structures were elucidated through comprehensive 1D and 2D NMR, UV, IR, and HRMS analyses. Bioassay results showed all the three compounds had obviously cell-protective effects against H2O2-induced H9c2 cardiomyocytes injury in a concentration -dependent manner.

KEYWORDS
  • Achyranthes bidentata
  • isoflavonoid glycosides
  • antioxidant activity

SUPPORTING INFORMATION


New compounds search report of SciFinder
Download File SciFinder-new compound.docx (645.59 KB)
Supporting Information
Download File 257-RNP-2104-2039-SI.pdf (630.55 KB)