JOURNAL 3196


Records of Natural Products
VOLUME & ISSUE
Available Online: May 30,2024
PAGES
p.1 - 5
DOI ADDRESS
http://doi.org/10.25135/rnp.461.2404-3196
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Yongbang Zhu
  • Xuan Zheng
  • Weiqiang Fei
  • Daoxian Ding
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new bisabolane sesquiterpenoid, named calkbisabenacid (1), was isolated from the leaves of Callicarpa kwangtungensis, along with four known compounds: 5-O-coumaroylquinic acid (2), kaempferol (3), and soyasapogenol B (4). The structure of compound 1 was determined by 1H NMR, 13C NMR, COSY, HSQC, and HMBC spectra, in combination with the HRESIMS data. The absolute configuration of C-1 in compound 1 was determined by comparing the experimental ECD spectrum with the calculated ECD spectra of the two possible stereoisomers. The known compounds were identified by comparing their NMR data with those reported in the literature. Compound 4 was isolated from this species for the first time. None of these compounds demonstrated any inhibitory effects against Staphylococcus aureus ATCC 25923.

KEYWORDS
  • Calkbisabenacid
  • Sesquiterpene
  • Callicarpa kwangtungensis

SUPPORTING INFORMATION


Supporting Information
Supporting Information
Download File Supporting Information-R1.docx (1.18 MB)