JOURNAL 1971


Records of Natural Products
VOLUME & ISSUE
Available Online: May 01,2021
PAGES
p.1 - 10
DOI ADDRESS
http://doi.org/10.25135/rnp.246.21.02.1971
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Esengül Karahisar
  • Yavuz Bülent Köse
  • Gökalp İşcan
  • Mine Kürkçüoğlu
  • Osman Tugay
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


The chemical compositions and anticandidal activities of the essential oils from the aerial parts, inflorescence, and roots of the endemic P. heyniae H. Duman & M. F.Watson were evaluated. Hydrodistillation was used to isolate the essential oils and the chemical analyses were performed both by GC-FID and GC/MS, respectively. Forty-four compounds constituting 94.4% of aerial parts, thirty-nine compounds constituting 99.5% of inflorescence, and twenty-five compounds representing 100.0% of root essential oil were characterized. The main compounds of the aerial parts oil were elemol (36.2%), b-bisabolenal (14.1%), and germacrene D (12.7%). Main compounds of inflorescence oil were b-bisabolenal (21.6%) germacrene D (15.6%), and germacrene B (12.4%) while the roots oil were a-pinene (44.8%), limonene (15.3%), b-pinene (12.5%), and d-3-carene (10.2%), respectively. The in vitro anticandidal activity of the essential oils were evaluated against several Candida strains by using partly modified CLSI broth microdilution method M27-A2. The tested essential oil showed relatively weak effects against pathogenic Candida strains compared to standard antifungal agents.

KEYWORDS
  • Apiaceae
  • essential oil
  • GC/MS
  • Prangos heyniae
  • anticandidal activity