Chemical Constituents from the Roots of Rehmannia glutinosa

Original Article

JOURNAL 2625

Records of Natural Products
VOLUME & ISSUE
Available Online: February 14,2023
PAGES
p.1 - 7
DOI ADDRESS
http://doi.org/10.25135/rnp.380.2211.2625
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Penghua Shu
  • Shujing Cai
  • Xiaojian Zhao
  • Shuo Zang
  • Ruihua Li
  • Yabing Ge
  • Xiaoqing Lu
  • Xialan Wei
  • Yuan Yang
  • Haitang Yang
  • Na Sun
PDF OF ARTICLE

GRAPHICAL ABSTRACT

ABSTRACT

Ten secondary metabolites, including one new monoterpene rhamnoside (1), five terpenoids (2–6), two nucleosides (7–8), and two phenylethanoid glycosides (9–10) were isolated from the roots of Rehmannia glutinosa. Their structures were determined by spectroscopic analysis such as NMR and HR-ESI-MS. In the tyrosinase inhibitory assay, compounds 2, 6 and 8 showed inhibition against tyrosinase. Compounds 1, 4, 5, 6, 9 and 10 are being reported in the genus Rehmannia for the first time.

 KEYWORDS
  • Rehmannia glutinosa
  • rhamnoside
  • phenylethanoid glycoside
  • tyrosinase

SUPPORTING INFORMATION

Supporting Information
Download File 380-RNP-2211-2625-SI.pdf (1.95 MB)