JOURNAL 2073


Records of Natural Products
VOLUME & ISSUE
Available Online: July 23,2021
PAGES
p.1 - 5
DOI ADDRESS
http://doi.org/10.25135/rnp.268.2105.2073
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
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AUTHORS
  • Peng Wang
  • Chenpeng Liu
  • Sun Wanying
  • Lei Yang
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


A new alkaloid, named scopariaine A (1), was obtained from the whole plant of Scoparia dulcis L. The new structure was established by various spectroscopic tmethods including 1D (1H-, 13C-NMR), 2D-NMR (HMBC, HSQC) and high resolution electrospray ionization mass spectrometry (HR-ESI-MS). Scopariaine A (1) was tested for its protective effect on attenuating palmitate-induced viability at 5, 10 and 25 μM. The results showed that the cell viability was increased in palmitic acid combined with scopariaine A (1) treated H9C2 cells.

KEYWORDS
  • Scoparia dulcis L.
  • scopariaine A
  • alkaloid
  • H9C2 cells

SUPPORTING INFORMATION


Supporting Information
Download File 268-RNP-2105-2073-SI.pdf (828.8 KB)