JOURNAL 2399


Records of Natural Products
VOLUME & ISSUE
Available Online: June 21,2022
PAGES
p.1 - 5
DOI ADDRESS
http://doi.org/10.25135/rnp.336.2203.2399
(DOI number will be activated after the manuscript has been available in an issue.)
STATISTICS
Viewed 86 times.
AUTHORS
  • Xiuxia Yang
  • Xishan Bai
  • Hongrui Li
  • Jingxian Sun
  • Yong Xiong
  • Yanhong Li
  • Xiangzhong Huang
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


Phytochemical investigation of Psammosilene tunicoides led to isolation of a new cyclic peptide, psammosilenin C (1) and three known compounds, 1-O-(β-D-glucopyranosyl)-(2S,3R,4E,8E)-2-[(2R)-2-hydroxypentadecanoylamino]-4,8-octadecadiene-1,3-diol (2), dihydroferulic acid (3) and vanillylacetone (4). Their structures were elucidated by comprehensive spectroscopic methods, including 1D and 2D NMR spectroscopic, and HR-ESI-MS spectrometric data. Compounds 1, 2 and 4 showed inhibitory activities on lipopolysaccharide (LPS)-induced NO release in RAW 264.7 cells.

KEYWORDS
  • Psammosilene tunicoides
  • cyclic peptide
  • anti-inflammatory activity