JOURNAL 1124
Bioorganic and Medicinal Chemistry Reports
Year: 2018 Issue: 1 January-December
p.16 - 21
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GRAPHICAL ABSTRACT
ABSTRACT
Citric acid is an inactive ingredient that is widely used in pharmaceutical, cosmetic and food industries. It is an organic acid that is produced during the Krebs cycle of the cell metabolism therefore it is present in the living organisms. Natural resource of the citric acid is citrus fruits and it is well known for its preservative action. Synthetically by utilizing from biotechnological tools, it can be produced by Aspergillus niger in a media that can supply the sµgar source. In this study we compared the efficiencies of carob molasses and potato based broths to grow A. niger for citric acid production. Carob molasses are widely found in the region and their utilization as media in biotechnological production of the citric acid would be advantageous. Our results support that this media can be used as an efficient source for the citric acid producing fungus A. niger in the bioreactors.
KEYWORDS- Microbiology
- Biotechnology
- Citric acid
- Carob
- Pharmaceutical industry
- Cosmetics
