Records of Natural Products

A scientific open access journal in the field of natural products.
Editor-in-Chief: Gülaçtı Topçu
Honorary Editor: Ayhan Ulubelen
Co-Editor-in-Chief: Ahmet C Gören

LATEST ARTICLES

Short Report

3-O-Formyl -27-Hydroxyfusidic Acid: A New Metabolite of Fusidic Acid by Cunninghamella echinulata

Rec. Nat. Prod. (2020) in press ; 1 - 5
by Amany Elsayed Ragab , Abdel-rahim Sayed Ibrahim and Francisco Léon

Minor metabolites of  Fusidic acid (1) using the fungus Cunninghamella echinulata NRRL 1382 were investigated for discovering previously unstudied reactions. An unprecedented fusidic acid derivative, C-27-hydroxy-3-O-formyl fusidic acid (2) was isolated, and its chemical structure was fully elucidated using various spectroscopic techniques including 1D, 2D NMR and HRESIMS. This is the first report for formylation reaction by C. echinulata.

DOI
http://doi.org/10.25135/rnp.168.19.12.1505
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Fusidic acid Cunninghamella echinulata 3-O-Formylation
Available online: February 18, 2020
DETAILS DOWNLOAD PDF
© ACG Publications. All rights reserved.
Original Article

Two New Alkaloids from Pleurotus ostreatus (Jacq. :Pers.) Roll

Rec. Nat. Prod. (2020) in press ; 1 - 7
by Lijie Zhu , Xianwei Han , Xiao Cui , Shuang Li , Liman Qiao and Ruijie Chen

Pleurotus ostreatus (Jacq. :Pers.) Roll is a grey edible mushroom (Agaricochaete), containing a variety of vitamins, minerals and different kind of secondary metabolites. Two new terpenoid indole alkaloids (Terpendole N and Terpendole O) were isolated from the fermentation of P. ostreatus. Their structures were elucidated by 1D, 2D NMR, HR-ESI-MS, and ECD.

DOI
http://doi.org/10.25135/rnp.166.19.11.1480
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Pleurotus ostreatus (Jacq. :Pers.) Roll alkaloids spectroscopic analyses
Available online: February 17, 2020
DETAILS DOWNLOAD PDF
© ACG Publications. All rights reserved.
Short Report

Cytotoxic Lathyrane Diterpenoids from the Roots of Euphorbia fischeriana

Rec. Nat. Prod. (2020) in press ; 1 - 6
by Jue Li , Jianlin He , Chunai Yang , Xuelong Yan and Zhao Yin

Two new lathyrane diterpenoids, euphofischers A and B (1 and 2), along with three known analogues (3-5), were isolated from the roots of Euphorbia fischeriana. Their structures were elucidated by spectroscopic analysis. Euphofischer A (1) represents rare example of a lathyrane diterpenoid featuring a 15-p-coumaroyl moiety. All compounds were screened for their cytotoxicity against three cancer cell lines (C4-2B, C42B/ENZR, and MDA-MB-231), and  compound 1 exhibited significant cytotoxicity against C4-2B cell line, with an IC50 value of 11.3 mM.

DOI
http://doi.org/10.25135/rnp.167.19.12.1496
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Euphorbia fischeriana Euphorbiaceae lathyrane diterpenoid
Available online: February 17, 2020
DETAILS DOWNLOAD PDF
© ACG Publications. All rights reserved.
Short Report

A New 4,5-Secofurancadinene from the Rhizome of Curcuma kwangsiensis

Rec. Nat. Prod. (2020) in press ; 1 - 4
by Weifeng Dai , Lianli Zhang , Yanfang Liu and Mi Zhang

The rhizome of Curcuma kwangsiensis S. G. Lee et C. F. Liang is a Traditional Chinese Medicine indexed in Chinese Pharmacopoeia. A new compound, 4,5-seco-pyrocurzerenone (1), was isolated from the species along with sixteen sesquiterpenoids (2-17). Their structures were elucidated based on the spectroscopic evidence, mainly including NMR and HRESIMS. All the compounds were reported for the first time from this species.

DOI
http://doi.org/10.25135/rnp.169.20.01.1520
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Sesquiterpenoid 4,5-secofurancadinene Curcuma kwangsiensis
Available online: February 17, 2020
DETAILS DOWNLOAD PDF
© ACG Publications. All rights reserved.