Records of Natural Products

A scientific open acces journal in the field of natural products.
Editor-in-Chief: Gülaçtı Topçu
Honorary Editor: Ayhan Ulubelen
Co-Editor-in-Chief: Ahmet C Gören

LATEST ARTICLES

Original Article

A New Heliquinomycin Analogue with Immunosuppressive Activity from Streptomyces sp. jys28

Rec. Nat. Prod. (2019) in press ; 1 - 6
by Can Su , Chongxi Liu , Yongjiang Wang , Wen-sheng Xiang , Chenggang Zou and Sheng-Xiong Huang

Heliquinomycin (1) and a new analogue 9′-methoxy-heliquinomycin (2) were isolated from the culture broth of Streptomyces sp. jys28. The structure of new analogue was elucidated by comprehensive analyses of HR-ESI-MS and NMR spectroscopic data. Among them, Heliquinomycin (1) showed immunosuppressive and antibacterial activities.

DOI
http://doi.org/10.25135/rnp.123.18.12.1085
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Heliquinomycin Immunosuppressive activity Antibacterial activity
Available online: April 11, 2019
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© ACG Publications. All rights reserved.
Original Article

First Report on Volatile Composition of Tricholoma anatolicum in Comparison with Tricholoma caligatum

Rec. Nat. Prod. (2019) in press ; 1 - 10
by Hatıra Taşkın , Zeynep Dilan Çelik , Fuat Bozok , Turgut Cabaroğlu and Saadet Büyükalaca

Tricholoma anatolicum collected from Turkey is consumed by public and exported to Japan every year. It was previously identified as Tricholoma caligatum until it was recognized as a new species. In the existing literature, there is no information on the aromatic composition of T. anatolicum. Therefore, in this study it was aimed to identify the volatile composition of T. anatolicum together with T. caligatum. Species identification was confirmed using molecular analyses based on ITS rDNA sequencing. Volatile compounds of both mushroom species were extracted using liquid-liquid extraction method and determined by Gas Chromatography-Mass Spectrometry-Flame Ionization Detector (GC-MS-FID). In the two Tricholoma species, 31 volatiles were obtained and grouped in seven chemical classes. The amounts of alcohols, volatile acids and esters were found to be higher in T. anatolicum, whereas the amounts of terpenes were detected as higher in T. caligatum. 1-Octen-3-ol responsible for the mushroom-like odour was only found in T. anatolicum.

DOI
http://doi.org/10.25135/rnp.122.18.12.1095
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Tricholoma anatolicum Tricholoma caligatum Tricholomataceae volatile aroma composition Turkey
Available online: April 11, 2019
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Original Article

A New Aporphine Alkaloid from Illigera aromatic

Rec. Nat. Prod. (2019) in press ; 1 - 6
by Kui-Wu Wang , Xiaoxin Wang , Haijiang Zhang and Yichao Ge

Chemical investigation of the aerial part of Illigera aromatic S.Z. Huang & S.L. Mo has resulted in the isolation and characterization of one new aporphine alkaloid, illigerine B (1), along with three known analogues laurodionine B (2), N-formyl-laurolitsine (3) and illigerine A (4). Their structures were established by spectrometric means and physico-chemical properties. The in vitro cytotoxic activities of compound 1 against Hela, SMMC7721, and Bcap37 cell lines were evaluated. Compound 1 exhibited moderate cytotoxic activity against the three tumor cell types, with IC50 values of 12.40 ± 0.78, 32.61 ± 2.05, and 28.69 ± 1.80 μg/mL. This work shown that aporphine alkaloids might be useful as characteristic markers in chemotaxonomic research of the genus Illigera.

DOI
http://doi.org/10.25135/rnp.121.18.11.1033
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Hernandiaceae Illigera aromatic Aporphine alkaloid lligerine B Cytotoxicity
Available online: April 02, 2019
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Original Article

A New Isoflavonolignan Glycoside from Abrus cantoniensis

Rec. Nat. Prod. (2019) in press ; 1 - 6
by Fuxuan Wu , Miaomiao Yu , Wanling Chen , Lu Zhou , Dan Zhang , Yujie Peng , Xifeng Sheng , Hui Zou and Junjiang Fu

A new isoflavonolignan glycoside, namely cantoniensin A (1), along with three known compounds were isolated from Abrus cantoniensis. The structure of the new compound was elucidated on the basis of spectroscopic analyses, including 1D-, 2D-NMR and HRESIMS. Compound 1 is the second example of isoflavonolignan glycoside from nature and is also the first isoflavonolignan isolated from the genus of Abrus.

DOI
http://doi.org/10.25135/rnp.125.19.01.1165
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Leguminosae Abrus cantoniensis cantoniensin A isoflavonolignan isoflavonolignan glycoside
Available online: March 02, 2019
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