Records of Natural Products

A scientific open acces journal in the field of natural products.
Editor-in-Chief: Gülaçtı Topçu
Honorary Editor: Ayhan Ulubelen
Co-Editor-in-Chief: Ahmet C Gören

LATEST ARTICLES

Original Article

Secondary Metabolites of Ethanol Extracts of Pinus sylvestris Cones from Eastern Anatolia and Their Antioxidant, Cholinesterase and α-Glucosidase Activities

Rec. Nat. Prod. (2019) in press ; 1 - 10
by Meryem Topal

Scots pine (Pinus sylvestris) is the most widely distributed tree species among pine species.  Antiradical, antioxidant properties and inhibition properties on butyrylcholinesterase (BChE), acetylcholinesterase (AChE) and α-glycosidase activities of ethanol extracts of P. sylvestris were reported from  Sarikamis (Kars),  Gumushane and Erzurum provinces of  Turkey.  The cones of  P. Sylvestris from Gumushane showed the highest IC50 values in both DPPH. (14.75 µg/mL) and ABTS.+ (12.56 µg/mL) radical scavenging activities. An LC-HRMS method  developed and the secondary metabolite composition of extracts were identified.  The major  compounds are  determined as (+)-trans taxifolin, quercitrin, fumaric acid, (-) epicatechin, and nepetin-7-O-glucoside, apigenin-7-O-glucoside in P. sylvestris cones.

DOI
http://doi.org/10.25135/rnp.155.19.06.1326
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Pinus sylvestris acetylcholinesterase butyrylcholinesterase antioxidant activity α-glucosidase LC-HRMS
Available online: November 12, 2019
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Short Report

Diterpenoids and Sesquiterpenoids from Syzygium fluviatile

Rec. Nat. Prod. (2019) in press ; 1 - 5
by Dingli Zhang , Yikao Hu , Li Wang , Sheng-Xiong Huang , Yan Zhao , Mengjia Li , Feng Li and Zhao Yong Zhao

Abstract:  A new monocyclic diterpenoid, cassipouryl formate, (1) together with three known diterpenoids (24) and five known sesquiterpenoids (59) were isolated from the twigs and leaves of Syzygium fluviatile. The new isolate was elucidated by various spectroscopic technologies. This was the first example of the chemical constituents from this species and the first report on the diterpenoids from genus Syzygium.

DOI
http://doi.org/10.25135/rnp.158.19.08.1393
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Syzygium fluviatile Myrtaceae diterpenoids sesquiterpenoids.
Available online: November 11, 2019
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Short Report

Two New 2(1H)-Pyrazinone Derivatives from the Plant Endophyte Streptomyces sp. KIB-H1992

Rec. Nat. Prod. (2019) in press ; 1 - 5
by Xiao-yan Ma , Zhouxin Zhang , Li Wang , Xinjun Hu , Xingyong Liu and Sheng-Xiong Huang

Two new 2(1H)-pyrazinone derivatives, 3,6-diisopropyl-5-methylpyrazin-2(1H)-one (1) and 5-(hydroxymethyl)-3,6-diisopropylpyrazin-2(1H)-one (2), were isolated from the fermentation broth of endophytic actinomycete Streptomyces sp. KIB-H1992. Their structures were established based on the detailed spectroscopic analyses, including ESI-MS, HR-ESI-MS, 1D- and 2D NMR spectra.

DOI
http://doi.org/10.25135/rnp.154.1907.1355
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
2(1H)-pyrazinone derivatives endophytic actinomycete Streptomyces sp. spectroscopic analyses
Available online: November 05, 2019
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Original Article

α-Pinene, Caryophyllene and β-Myrcene from Peucedanum terebinthaceum Essential oil: Insecticidal and Repellent Effects on Three Stored-Product Insects

Rec. Nat. Prod. (2019) in press ; 1 - 13
by Jiansheng Sun Sun , Yixi Feng , Yang Wang , Jigang Li , Kexing Zou , Hong Liu , Yichao Hu , Yun Xue , Longyan Yang , Shu-shan Du and Yan Wu

The aim of this work was to evaluate the bioactivities of Peucedanum terebinthaceum (Fisch.) Fisch. ex Turcz. essential oil and its three second rich constituents against Tribolium castaneum Herbst, Lasioderma serricorne Fabricius and Liposcelis bostrychophila Badonnel. The essential oil from aerial part of P. terebinthaceum was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. Thirty-three constituents were confirmed by GC-MS, which accounting for 91.5% of the total oil. The principal constituents included β-thujene (21.4%), β-terpinene (11.8%), germacrene D (9.4%) and dihydro-cis-α-copaene-8-ol (8.0%). Besides, β-myrcene (6.2%), Linalyl isovalerate (4.3%), α-pinene (4.0%), caryophyllene (3.6%), (Z)-α-farnesene (3.6%) and β-elemene (3.0%) were also detected in relatively lower content. The essential oil possessed promising potential in pest control, as it showed strong contact toxicity and repellent effects on T. castaneum and L. serricorne. Three major constituents α-pinene, caryophyllene and β-myrcene were toxic to three insect species in contact assays and showed repellent effects on T. castaneum and L. bostrychophila. This work revealed the insecticidal capacity of P. terebinthaceum and would provide some information for the development of new strategies in the control of insect pests.

DOI
http://doi.org/10.25135/rnp.149.19.05.1287
(DOI number will be activated after the manuscript has been available in an issue.)
Keywords
Fumigant toxicity Contact toxicity Tribolium castaneum Herbst Lasioderma serricorne Fabricius Liposcelis bostrychophila Badonnel
Available online: October 14, 2019
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