Quantification of main secondary metabolites of Satureja icarica P.H. Davis (Lamiaceae) by LC-HRMS and evaluation of antioxidant capacities

Original Article

JOURNAL 2956

Journal of Chemical Metrology

VOLUME & ISSUE

Year: 2023 Issue: 2 July-December

PAGES

p.199 - 214

DOI ADDRESS

http://doi.org/10.25135/jcm.2311.2956

STATISTICS

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AUTHORS

Betül Kiraz Kinoğlu
Tuncay Dirmenci
Saleh H. Alwasel
İlhami Gülçin
Ahmet C. Gören

GRAPHICAL ABSTRACT

ABSTRACT

In this study, we determined antioxidant activity of Satureja icarica (Lamiaceae) which is used as a spice by the local population against 1,1-diphenyl-2-picryl-hydrazyl (DPPH·), N,N-dimethyl-p-phenylenediamine radicals (DMPD•+), and 2,2-azino-bis-3-ethylbenzthiazoline-6-sulfonic acid (ABTS•+) as well as their ability to reduce Fe3+, Fe3+-TPTZ, and Cu2+. The antioxidant activities of both extracts were similar to those of standards in all assays. For instance, IC50 of S. icarica were for scavenging DPPH was 10.19 μg/mL. The results of liquid chromatography-high resolution mass spectrometry (LC-HRMS) revealed that the main secondary metabolites in Satureja icarica were found to be as rosmarinic acid and luteolin-7-O-rutinoside.

KEYWORDS

Satureja icarica
LC-HRMS
seconder metabolite
antioxidat activity
rosemarinic acid