JOURNAL 3156
Journal of Chemical Metrology
Year: 2024 Issue: 1 January-June
p.83 - 94
Viewed 522 times.
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Reham El Nagar
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Ahmed I. Abou-Kandil
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Eman M. Shoukry
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Hayam M. Ahmed
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Randa Yamani
GRAPHICAL ABSTRACT
ABSTRACT
Abstract: In the current project, the National Institute of Standards (NIS), Egypt, initiated a preliminary investigation to create a certified reference material for certain elements, including Fe, Mg, Mn, Al, Cu, and Zn, in human hair. This reference material would be a quality control sample for trace element determination. This paper studied homogeneity and short-term stability as key parameters for producing certified reference materials. ICP-OES and AAS were used to measure human hair powder samples, and the data was statistically evaluated for normality and outliers, which resulted in the measurement results being normal after removing the outliers. Also, sample homogeneity was evaluated and assessed using analysis of variance (ANOVA), which revealed that the human hair samples produced were homogenous and stable during transportation. This CRM mainly intends to develop methods and check instrumental performance, analytical trueness, and accuracy-related to trace element analysis in human hair and similar matrices.
KEYWORDS- Biological samples
- reference materials
- homogeneity
- stability
- elemental analysis
- ICP-OES
