JOURNAL


Organic Communications
VOLUME & ISSUE
Year: 2019 Issue: 1 (January-March)
PAGES
p.1 - 13
STATISTICS
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AUTHORS
  • Furqan Diwan
  • Mubarak H. Shaikh
  • Mohammad Shaikh
  • Mazahar Farooqui
  • 1 - Scientist
  • 2 - Scientist
  • 3 - Scientist
  • 4 - Principal Dr Rafik Zakariya Womens college Navkhanda.
PDF OF ARTICLE

ABSTRACT


A new and efficient protocol was developed for synthesis of benzothiazoles as a potential antimicrobial and antioxidant agent using γ-Valerolactone (GVL) as catalyst and solvent under environmentally friendly conditions. The developed synthetic protocol represents a very simple and novel route for the synthesis of 2-substituted benzothiazole derivatives. In addition, an ultrasound irradiation technique is successfully implemented for carrying out the reactions in shorter reaction times. The synthesized benzothiazoles were evaluated for antimicrobial and antioxidant activity and also analyzed for ADME properties.

KEYWORDS
  • γ-Valerolactone (GVL)
  • benzothiazoles
  • antimicrobial
  • antioxidant
  • ADME prediction
  • ultrasound irradiation

SUPPORTING INFORMATION


Supporting Information
Download File 1-54-OC-1902-1212-SI.pdf (1.35 MB)