JOURNAL 1551


Organic Communications
VOLUME & ISSUE
Year: 2020 Issue: 1 January-March
PAGES
p.28 - 32
STATISTICS
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AUTHORS
  • Parshuram M. Pisal
  • Ajay S. Sawant
  • Vinod T. Kamble
  • Ravi Varala
  • Syed F. Adil
  • Mujeeb Khan
  • Mohammed Rafiq H. Siddiqui
PDF OF ARTICLE

GRAPHICAL ABSTRACT


ABSTRACT


In this study, zirconium tetrachloride is used as a highly efficient catalyst for the one-pot three component reaction of 3,4-dihydro(2H)-pyran, urea and benzaldehyde in ethanol, producing corresponding hexahydropyrano pyrimidinone derivatives in good yields, with excellent diastereoselectivity. This method has various benefits such as easy availability of starting materials, lower cost, higher yield and shorter reaction time.

 

 

KEYWORDS
  • Multi-component reactions
  • aldehydes
  • urea/thiourea
  • 3,4-dihydro(2H)-pyran
  • atalysis

SUPPORTING INFORMATION


Supporting Information
Download File A5-72-OC-2002-1551-SI.pdf (958.98 KB)